Washington: Wouldn’t it be nice if we could eat all of the sugar and fat that we want without gaining a pound.It may be possible and it’s not far from reality as researchers from the United States and Europe have found that blocking one of three opioid receptors in your body could turn your penchant for sweets and fried treats into a weight loss strategy that actually works.By blocking the delta opioid receptor, or DOR, mice reduced their body weight despite being fed a diet high in fat and sugar.The scientists believe that the deletion of the DOR gene in mice stimulated the expression of other genes in brown adipose tissue that promoted thermogenesis.“Our study provided further evidence that opioid receptors can control the metabolic response to diets high in fat and sugar, and raise the possibility that these gene products (or their respective pathways) can be targeted specifically to treat excess weight and obesity,” said Traci A. Czyzyk, Ph.D., a researcher involved in the work from the Department of Physiology at the Mayo Clinic in Scottsdale, Arizona.
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