Washington: A new clinical research by University at Buffalo endocrinologists has shown that a low dose of insulin can suppress the expression in the blood of four precursor proteins involved in the pathogenesis of Alzheimer`s disease.The research suggests that insulin could have a powerful, new role to play in fighting Alzheimer`s disease."Our results show clearly that insulin has the potential to be developed as a therapeutic agent for Alzheimer`s, for which no satisfactory treatment is currently available," said Paresh Dandona, UB distinguished professor of medicine in the School of Medicine and Biomedical Sciences and senior author on the study.
"If this effect of insulin proves, in larger studies, to be systemic, then insulin may well be a potential therapeutic agent in treating Alzheimer`s disease. The challenge is to deliver insulin directly into the brain, thus avoiding its hypoglycemic effect," he added.The study has been published in the Journal of Clinical Endocrinology and Metabolism. ANI
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