Insulin pills for diabetics may make painful jabs history
Washington: Good news for diabetics on insulin: After years of research, insulin pills that could make it easier for patients to manage diabetes are finally moving ahead in clinical trials.
The new development may soon make painful insulin jabs a thing of the past.
The topic has been highlighted in the current issue of Chemical & Engineering News (C&EN), ACS`` weekly newsmagazine.
C&EN Senior Correspondent Ann Thayer notes that drug manufacturers have tried for years to develop oral insulin without much success.
Insulin is a peptide hormone that people with diabetes currently take by injection to bring their blood sugar to within normal levels.
But doing so requires uncomfortable, inconvenient injections that can make patients reluctant to use the drug frequently enough to adequately control their blood sugar. An oral form of insulin could help solve this problem.
However, stomach acids and enzymes easily destroy insulin and other protein-based drugs. Scientists have had difficulty finding an effective way to eliminate this problem.
They``ve responded to this challenge by developing special coatings for insulin pills that prevent stomach acid from destroying them.
Scientists also are using additives that make it easier for the intestine to absorb large molecules like insulin.
After years of setbacks, signs of success may be at hand. Several insulin pills are now in various stages of clinical trials, and proof of concept may allow them to move into late-stage and more rigorous clinical testing.
However, only time will tell whether these much-anticipated pills will make it to the market?
More from India
More from World
More from Sports
More from Entertaiment
- Sheena murder: Trio to be taken to Raigad to re-construct crime scene
- Mikhail emailed sister Sheena Bora's resignation letter: Report
- Raksha Bandhan: Sushma Swaraj ties Rakhi to Venkaiah Naidu
- Shiv Sena announces award of 2 lakh for Hindu families with 5 kids
- Watch: Wife catches husband with his girlfriend at Goa Airport
- Women's hockey team seals Olympic spot after 36 years, creates history on Dhyan Chand's birthday
- Sushma Swaraj ties rakhi to M Venkaiah Naidu
- Know box-office report of Saif-Katrina's 'Phantom'
- Indrani Mukerjea's son Mikhail emailed Sheena Bora's resignation letter
- Ten interesting facts about hockey legend Dhyan Chand