Washington: Healthy young people who put on as little as 9 pounds of fat, specifically in the abdomen, are at risk for developing endothelial cell dysfunction, Mayo Clinic researchers have found. Endothelial cells line the blood vessels and control the ability of the vessels to expand and contract.
Once the volunteers lost the weight, the blood flow recovered. Blood flow regulation was unchanged in the weight-maintainers and was less affected among those who gained weight evenly throughout their bodies. Dr. Somers says the study is unable to offer conclusions about whether recovery of blood flow is possible if the weight is kept on for several years. "Patients should know that having a big belly may be more harmful than simply being obese," he says. "Letting weight creep on during college or as the result of aging should not be accepted as normal. "Physicians should know that the location of fat is important. Greater attention should be given to the circumference of a patient’s waistline, not just their body mass index (BMI)." BMI is a formula that uses height and weight to estimate body fat and associated health risks. The study was published in this week’s Journal of the American College of Cardiology. ANI
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