London: Scientists at Oregon Health and Science University have become the first to grow liver stem cells in culture.For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions.But no lab in the world has been successful in identifying and growing liver stem cells in culture -- using any available technique - until now.Now, physician-scientists in the Pape Family Pediatric Research Institute at OHSU Doernbecher Children`s Hospital, Portland, Ore., along with investigators at the Hubrecht Institute for Developmental Biology and Stem Cell Research, Utrecht, Netherlands, have described a new method through which they were able to infinitely expand liver stem cells from a mouse in a dish.
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