London: Lower levels of an enzyme called p35, which is vital for activating a protein called Cdk5 for brain development, may be linked with schizophrenia.Professor Giese, Institute of Psychiatry at King`s College, London, said: "For the first time we have found that an enzyme activator called p35 is reduced in patients with schizophrenia.""Mice, genetically engineered to have lower levels of p35, developed cognitive impairment typical for this disease. This gives us a better understanding of the changes that occur in the brain during the onset of schizophrenia," added Giese.
However, many of the antipsychotic drugs or major tranquillizers used to treat or manage the illness have very bad side effects. IANS
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