Washington: Scientists have developed a mathematical model reflecting how red blood cells change in size and hemoglobin content during their four-month lifespan.
For example, it appears that RBCs from healthy individuals are cleared from the bloodstream before they shrink beyond a specific size. But in patients with mild iron-deficiency anemia or a genetic condition called thalassemia trait, RBCs continue shrinking past the clearance threshold for healthy cells.By looking for an increasing population of small RBCs in blood samples from individuals who had a normal blood test and then went on to develop iron-deficiency anemia 30 to 90 days later, the investigators were able to predict the development of iron-deficiency anemia."Looking for the initial shifting of this threshold may allow us to identify a developing anemia significantly earlier than we can now," Higgins says.The study has been published online in PNAS Early Edition. ANI
Rahul Gandhi addresses FICCI meet
Environment Minister Natarajan resigns
Adarsh scam: A tale of greed and nepotism?
Lieutenant Governor Najeeb Jung recommends President`s rule in Delhi