Neuron growth causes loss of early childhood memories
Toronto: Formation of new neurons in the hippocampus - a brain region known for its importance in learning and remembering - may be the reason why we have no memories from our earliest years, scientists claim.
Researchers have long known of the phenomenon of infantile amnesia. This refers to the absence of long-term memory of events occurring within the first 2-3 years of life, and little long-term memories for events occurring until about 7 years of age.
Studies have shown that though young children can remember events in the short term, these memories do not persist.
The new study by Drs Paul Frankland and Sheena Josselyn, from the Hospital for Sick Children in Toronto, shows that this amnesia is associated with high levels of new neuron production - a process called neurogenesis - in the hippocampus, and that more permanent memory formation is associated with a reduction in neurogenesis.
The researchers looked at retention of memories in young mice in which they suppressed the usual high levels of neurogenesis in the hippocampus (thereby replicating the circuit stability normally observed in adult mice).
In older mice they stimulated increased neurogenesis (thereby replicating the conditions normally seen in younger mice).
Frankland was able to show a causal relationship between a reduction in neurogenesis and increased remembering, and the converse, decreased remembering when neurogenesis increased.
"Why infantile amnesia exists has long been a mystery. We think our new studies begin to explain why we have no memories from our earliest years," Frankland said.
The results were presented at the 2013 Canadian Neuroscience Meeting, the annual meeting of the Canadian Association for Neuroscience - Association Canadienne des Neurosciences (CAN-ACN).
More from India
More from World
More from Sports
More from Entertaiment
- Is population control next on central govt's agenda after demonetization?
- Gujarat: Goods train engine catches fire in Surat
- Tamil Nadu CM Jayalalithaa's condition extremely grave
- Watch: Tracing the journey of late Tamil Nadu CM Jayalalithaa from films to politics
- Jayalalithaa's funeral procession: Sea of mourners gather to pay last respects
- RIP Amma: Jayalalithaa dies after 75 days in hospital; Tamil Nadu mourns
- Fake or Real? 'Alien animal' caught on Karnataka-Kerala border
- RBI to issue new Rs 100 banknotes, old notes to continue as legal tender
- Airtel’s free 4G internet offer may be a ploy to steal your data
- People want to know whether Jayalalithaa is alive or not; PM Narendra Modi must intervene, says expelled AIADMK MP Sasikala Pushpa