Washington: Researchers including an Indian origin have identified an entirely new approach to enhance normal tissue growth.Tissue regeneration is a process that is not fully understood, but previous research has demonstrated that endothelial cells lining the insides of small blood vessels play a key role in tissue growth. It is also known that these endothelial cells generate chemical messengers called epoxyeicosatrienoic acids (EETs), which stimulate blood vessel formation in response to tissue injury.In this new research, first author Dipak Panigrahy, MD, an investigator in Beth Israel Deaconess Medical Center (BIDMC) Center for Vascular Biology Research, and his colleagues wanted to find out how EETs might participate in organ and tissue regeneration. To find the answers, they created 7 different mouse models. The models focused on liver, kidney and lung regeneration; wound healing; corneal vascularization; and retinal vascularization.
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