London: A new research has shown that a little-studied amyloid peptide could play a greater role in promoting Alzheimer`s disease (AD), suggesting a potential role in new approaches for preventing AD-causing amyloidosis. One hypothesis that has attracted widespread support proposes that AD is caused by the buildup of the senile plaques, and in particular of their main constituent, amyloid-ß peptides (Aß). Two major forms of Aß, Aß40 and Aß42, have been associated with genetic mutations causing early-onset AD, and have thus received considerable research attention.
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