Washington: Scientists may have come across a new type of cancer immunotherapy, where they can harness body`s immune system to attack tumours.To accomplish this, they had to thread a needle in immune function, shrinking tumors without triggering unwanted autoimmune responses.The new research, performed in animals, is not ready for clinical use in humans. However, the approach, making use of a key protein to control immune function, lends itself to further study using candidate drugs that employ the same mechanisms.Study leader Wayne W. Hancock, M.D., Ph.D., of the Division of Transplant Immunology at The Children`s Hospital of Philadelphia (CHOP) said that this preclinical study demonstrates proof of principle that using a drug to regulate the function of a special, immunosuppressive subset of so-called T-regulatory (Treg) cells safely controls tumour growth.
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