London: Scientists claim to have developed a new technology which could free diabetics, cancer and HIV patients from daily and painful routine injections by releasing the required drug dosage over six months. Researchers from the University of Cambridge have developed injectable, reformable and spreadable hydrogels which can be loaded with proteins or other therapeutics and can last a maximum of six month. The hydrogels contain up to 99.7 per cent water by weight, with the remainder primarily made up of cellulose polymers held together with cucurbiturils, barrel-shaped molecules which act as miniature `handcuffs,` the journal Biomaterials reported. "The hydrogels protect the proteins so that they remain bio-active for long periods, and allow the proteins to remain in their native state," says Oren Scherman, a Cambridge chemist, who led the research. "Importantly, all the components can be incorporated at room temperature, which is key when dealing with proteins which denature (change their composition) when exposed to high heat," said Scherman in a statement.
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