London: British scientists claim to have achieved a major breakthrough by developing a drug which could kill deadly superbugs like C-diff and MRSA.C-Diff or Clostridium difficile is a life-threatening bacterium that causes diarrhoea and intestinal problems, while MRSA or Methicillin-resistant Staphylococcus aureus causes anumber of difficult-to-treat infections in humans. Both are acquired by patients in hospitals.
During tests, carriers of superbug bacteria had XF-73 gel placed inside their noses. The bugs were eradicated with no side effects, and MRSA did not show any resistance tothe new drug in clinical tests even after 55 repeat exposures. "This is a major breakthrough. Thousands of lives could be saved by destroying bugs in patients before they become susceptible to infections through medical proceduressuch as operations," said Dr Bill Love, the chief executive of Destiny Pharma, the pharmaceutical company behind the product. In fact, F-73 works differently from antibiotics by breaking down cell walls and causing the rapid loss of its vital contents. Antibiotics act by destroying specific partsof bacteria to disable them, a process that takes much longer. Prof Ian Chopra of Leeds University, an expert, said the development was "extremely exciting". "Resistance to antibiotics is seriously undermining the ability of medicalprofession to treat bacterial infections. "Society urgently requires the discovery and development of new anti-bacterial drugs that have a different method of action and minimal potential for the development ofresistance. XF-73 fulfils this need. The bactericidal potency of these drugs is remarkable," he said. PTI
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