Washington: In a major step towards gene therapy, scientists claim to have designed a new device – a nanoparticle -- which can effectively deliver genes into cells with minimal toxic effects.In laboratory experiments, a team at Ohio State University has found that this device, a vector, is able to deliver DNA deeply enough into cell to allow genetic materialto be activated -- a critical step in gene therapy. This vector is between two-and-a-half and 10 times more effective than other experimental materials, according to the scientists.
Nano refers to the tiny size of the particle in question -- its general structure can be detected only by an atomic force microscope. Calcium phosphate is a mineral found in bones and teeth. Lipids are fatty molecules that help maintain the structure of cell membranes. Together, they form a protectiveand inflexible structure that, thanks to complex chemical reactions, self-destructs once inside a cell. Bureau Report
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