Now, gene-altering moisturiser to fight skin cancer
London: Scientists at Northwestern University have supercharged moisturiser with gene-regulation technology to tackle skin cancer.
In case of skin conditions like melanoma, treatments that are applied directly to the skin are the ideal drug solution as they are easy to use and they affect only the area under which they are applied.
Our skin is such a successful barrier against toxins and so finding substances that penetrate it is a huge challenge, according Amy Paller at Northwestern University’s Feinberg School of Medicine in Chicago.
So until now, clinics have used lasers or ultrasound to help deliver drugs deep into the skin.
Now, Paller and her colleague Chad Mirkin, also at Northwestern, have found a way through the skin barrier.
They coated tiny gold spheres with small interfering RNA (siRNA) - tiny pieces of nucleic acid that appear to penetrate the barrier and enter skin cells through an as-yet unspecified pathway.
The siRNA is selected to target one of the genes responsible for making cancer cells grow quickly, called epidermal growth factor receptor.
“Nanoparticles are an all-in-one solution,” New scientist quoted Paller as saying.
Paller and Mirkin mixed the drug with shop-bought moisturiser and applied it to mouse skin.
They found that not only did the nanoparticles penetrate the skin, but they also targeted the intended gene without causing toxicity or other side effects in the surrounding skin.
Their study had been published in the Proceedings of the National Academy of Sciences.
More from India
More from World
More from Sports
More from Entertaiment
- Watch: Jayalalithaa's last rites performed by her close friend and aide Sasikala Natarajan
- Jayalalithaa's funeral procession: Sea of mourners gather to pay last respects
- Watch: Jayalalithaa's last rites performed by her close friend and aide Sasikala Natarajan - Part II
- DNA: Know why Jayalalithaa was buried and not cremated
- Panel discussion over continuous chaos in Parliament on demonetisation
- RIP Amma: Jayalalithaa dies after 75 days in hospital; Tamil Nadu mourns
- Twitter users blast Arvind Kejriwal as he says 'Modi will never appoint a Muslim Vice President no matter what Jung does'
- RBI to issue new Rs 100 banknotes, old notes to continue as legal tender
- Airtel’s free 4G internet offer may be a ploy to steal your data
- Kapil Sharma renews contract, his latest fee will make your jaw drop!