Georgia: Children with more body fat and less endurance have stiffer arteries at a very young age, researchers at Medical College of Georgia have said.
Stiff arteries are a hallmark of atherosclerosis, a typically adult condition in which blood vessels become clogged.
"When children at such a young age start getting diseases only adults used to get, it’s like the sky is falling," said Dr. Catherine L. Davis, clinical health psychologist in MCG’s Georgia Prevention Institute and principal investigator on the study.
The findings were presented during the 31st Annual Society of Behavioral Medicine Meeting.
Using a non-invasive measure of pulse wave velocity, Davis discovered that children with a greater body mass index, more body fat and less endurance had stiffer central arteries compared to leaner and fitter children. Identifying these children early could hasten preventive measures, she noted.
Her most recent National Heart, Lung and Blood Institute -funded study involves overweight or obese 8-11-year-old children, half of whom participate in aerobic exercises such as jumping rope and shooting hoops weekdays after school while the other half participate in sedentary activities, including board games and crafts.
Among a similar cohort of children, Davis also found that regular exercise decreases metabolic risks linked to cardiovascular disease and diabetes. The new study will examine the effects of exercise on nonalcoholic fatty liver disease and atherosclerosis.
Nonalcoholic fatty liver disease, which affects about 40 per cent of obese children, initially is often symptomless. But its long-term risk of inflammation and scarring, which can cause liver damage and failure, also is related to hardening of the arteries.
"It’s essentially another aspect of the metabolic imbalance these children are experiencing when they’re overweight and inactive and is a signal they’re at very high risk for diabetes," Davis said.