Rapid treatment after HIV infection `functionally cures about one in 10 patients`

Last Updated: Friday, March 15, 2013 - 17:08

London: Treatment as soon as HIV infection has been identified may be enough to “functionally cure” about a 10th of those diagnosed early, researchers in France have suggested.

The researchers said that 14 people who stopped therapy have since shown no signs of the virus resurging, the BBC reported.

The group of patients, known as the Visconti cohort, all started treatment within 10 weeks of being infected. They were given a course of antiretroviral drugs for three years, on average, but then stopped.

The drugs keep the virus only in check, but cannot eradicate it from its hiding places inside the immune system, the researchers said.

Normally, when the drugs stop, the virus bounces back. This has not happened in the Visconti patients and some have been able to control HIV levels for a decade.

Recently it was also reported that a baby girl has been effectively cured after very early treatment in the US.

Dr Asier Saez-Cirion, from the Institute Pasteur in Paris said theta most individuals who follow the same treatment will not control the infection, but there are a few of them who will.

He said 5-15 percent of patients might be functionally cured, meaning they no longer needed drugs, by attacking the virus soon after infection.

“They still have HIV, it is not eradication of HIV, it is a kind of remission of the infection,” he stated.

Writing in the journal PLoS Pathogens, the researchers explained that early treatment might limit the number of unassailable HIV hideouts that are formed.

However, they said it was “unclear” why only some patients were functionally cured.

Dr Andrew Freedman, a reader in infectious diseases at Cardiff University School of Medicine, said the findings were “certainly interesting”.

However, he cautioned that many patients would be diagnosed much later than in this study.

ANI



First Published: Friday, March 15, 2013 - 17:08

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