Washington: Researchers have discovered that the same MC1R genetic mutation that causes red hair also promotes a well-known cancer-causing pathway.Now researchers from Beth Israel Deaconess Medical Center (BIDMC) and Boston University School of Medicine (BUSM) have helped to explain the molecular mechanisms that underlie redheads` well-known risk of developing melanoma, providing new insights for treating and preventing this dangerous type of skin cancer. o-senior author Wenyi Wei, PhD, an investigator in the Department of Pathology at BIDMC and Associate Professor of Pathology at Harvard Medical School said that in this current study, they demonstrated that the mutation MC1R-RHC promotes the PI3K/Akt signaling pathway when a red-haired individual is exposed to UV radiation.
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