Regular exercise could keep Alzheimer’s at bay

London: Exercise raises levels of a brain molecule that may help protect against Alzheimer’s disease, a new research has shown.

Scientists believe the protein PGC-1alpha, which also appears to guard against type 2 diabetes, could lead to new treatments for treating Alzheimer’s.

Researchers studied brain samples from dead Alzheimer’s patients and from healthy people.

They found less PGC-1alpha in the Alzheimer’s-affected brains, reports the Daily Express.

Further investigation revealed that cells containing more PGC-1alpha produced less of the toxic amyloid protein that accumulates in the brains of people with the disease.

Since exercise boosts levels of PGC-1alpha, the findings may help explain the link between regular physical activity and reduced Alzheimer’s risk.

They also provide a clue to why diabetics are more likely to develop Alzheimer’s.

Magdalena Sastre, of Imperial College London, who led the study, said: “These early results have given us a potential treatment target.”


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