Revealed: How embryo develops into a beautiful you!
London: In path-breaking discovery, scientists have revealed the secret world of embryo development where it undergoes huge changes in a short space of time.
Termed 'black box' of development, scientists from University of Cambridge have found a new way to study and film this 'black box' during embryo implantation.
"We know a lot about pre-implantation, but what happens after implantation - and particularly the moment of implantation - is an enigma," said study author Professor Magdalena Zernicka-Goetz of University of Cambridge.
"During two days, the embryo goes from a relatively simple ball to a much larger, more complex cup-like structure. Exactly how that happens was a mystery, so we decided to develop a method that would allow us to culture and study embryos during implantation," she explained.
The new method would allow scientists to study embryo growth and development at implantation for the first time, which could help improve the success of in-vitro fertilisation (IVF).
Working with mouse cells, Professor Zernicka-Goetz and her colleague Dr Ivan Bedzhov succeeded in creating the right conditions outside the womb to study the implantation process.
They created a system comprising a gel and medium that, as well as having the right chemical and biological properties, was of similar elasticity to uterine tissue.
Crucially, this gel was transparent to optical light, allowing then to film the embryo during implantation.
This new method revealed that on its way from ball to cup, the blastocyst becomes a 'rosette' of wedge-shaped cells - a structure never before seen by scientists.
Embryo development in mammals occurs in two phases.
During the first phase called pre-implantation, the embryo is a small, free-floating ball of cells called a blastocyst.
In the second post-implantation phase, the blastocyst embeds itself in the mother's uterus.
"It's a beautiful structure. It's fascinating to see how these small cells organise so perfectly to allow us to develop," added Zernicka-Goetz.
The findings also mean developmental biology text books would need rewriting, said the study published in the journal Cell.
More from India
More from World
More from Sports
More from Entertaiment
- Soldier buried under Siachen avalanche snow rescued after six days
- Panel discussion on demand for expulsion of Wahabi Syllabus from Universities- Part IV
- DNA: Analysis on India's naval prowess at International Fleet Review
- Panel discussion on demand for expulsion of Wahabi Syllabus from Universities
- Panel discussion on demand for expulsion of Wahabi Syllabus from Universities- Part II
- 12 men rape British teen girl for over 13 months; slapped with 140 years in jail
- 'Achhe din': Residents of PM Modi's adopted village to get free electricity, work in full swing
- Siachen survivor Lance Naik Hanumanthappa brought to Delhi, Army chief Dabir Singh visits RR hospital
- Deepika Padukone, Vin Diesel in first ‘xXx: The Return of Xander Cage’ video – Watch
- How Lance Naik Hanumanthappa survived 6 days below 25 feet of snow in Siachen