Rogue gene causing breast cancer `discovered`

London: British scientists claim to have discovered a rogue gene which is responsible for breast cancer, a finding which may pave the way for new treatments for the most aggressive forms of the disease.

A team, led by Cancer Research UK`s Cambridge Research Institute, says it`s the first "oncogene" -- a dangerous gene promoting cancer growth -- pinpointed in five years, the
`Daily Express` reported.

Known as `ZNF703`, it could trigger up to one in 12 of all cases of breast cancer every year, affecting 4,000 patients. Although more tests are needed, the scientists believe it sends cells out of control.

Lead scientist Prof Carlos Caldas said: "Testing whether this gene is over-active in a tumour could help highlight those more likely to be resistant to standard hormone therapies."

Dr Lesley Walker of Cancer Research UK added: "This is exciting. It`s a prime candidate for developing new drugs specifically to target tumours in which this gene is over-active."

PTI

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