London: In a pioneering experiment, scientists have turned scar tissue, that forms after a heart attack, into heart muscles without using stem cells. An international team, led by Duke University Medical Center, has, in fact, used a new process which eliminates the need for stem cell transplant -- molecules called microRNAs to trigger the cardiac tissue conversion in a laboratory dish. And, for the first time, in a living mouse, the scientists demonstrated the potential of a simpler process for tissue regeneration, the `Circulation Research` journal said. If additional studies confirm the approach in human cells, it could lead to a new way for treating millions of people worldwide who suffer heart failure, which is often caused by scar tissue that develops after a heart attack. "This is a significant finding with many therapeutic implications. If you can do this in the heart, you can do it in the brain, the kidneys, and other tissues. This is a whole new way of regenerating tissue," Victor J Dzau, who led the team, said in a release.
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