Washington: Scientists have identified a brain receptor, an enzyme monoamine oxidase A, whose malfunctioning can trigger sudden violence, explosive outbursts and hostile overreaction to stress in mice.By blocking the receptor, which also exists in humans, scientists stripped the mice of their extreme aggressiveness, potentially paving the way to new treatment for severely aggressive behaviour.The findings by researchers from the University of Southern California (USC) and Italy are a significant breakthrough in developing drug targets for pathological aggression, a component in many common psychological disorders, including Alzheimer`s disease, autism, bipolar disorder and schizophrenia, the Journal of Neuroscience reports.
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