Washington: People with smaller regions of the brain’s cortex may be more likely to develop symptoms consistent with very early Alzheimer’s disease, a new study has suggested.“The ability to identify people who are not showing memory problems and other symptoms but may be at a higher risk for cognitive decline is a very important step toward developing new ways for doctors to detect Alzheimer’s disease,” said Susan Resnick, PhD, with the National Institute on Aging in Baltimore.For the study, researchers used brain scans to measure the thickness of regions of the brain’s cortex in 159 people free of dementia with an average age of 76.The brain regions were chosen based on prior studies showing that they shrink in patients with Alzheimer’s dementia.Of the 159 people, 19 were classified as at high risk for having early Alzheimer’s disease due to smaller size of particular regions known to be vulnerable to Alzheimer’s in the brain’s cortex, 116 were classified as average risk and 24 as low risk.At the beginning of the study and over the next three years, participants were also given tests that measured memory, problem solving and ability to plan and pay attention.
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