Washington: A study has found that smoking during pregnancy can lead to common birth defects like missing or deformed limbs, clubfoot, facial disorders and gastrointestinal problems.The study by scientists at UCL is the first comprehensive review to identify the specific birth defects (malformations) most associated with smoking.The authors examined a total of 172 research papers published over the last 50 years, which looked at a combined total of 174,000 cases of malformation alongside 11.7 million controls.The risk was increased by 26 percent for having a baby with missing or deformed limbs, 28 percent for clubfoot, 27 percent for gastrointestinal defects, 33 percent for skull defects, 25 percent for eye defects, and 28 percent for cleft lip/palate.The greatest increase in risk (50 percent) was for a condition called gastroschisis, where parts of the stomach or intestines protrude through the skin.The research authors recommend that public health guidance should now be more explicit about the specific malformations associated with maternal smoking, in order to try and reduce the numbers of pregnant women who smoke."People may think that few women still smoke when pregnant," lead author Professor Allan Hackshaw, UCL Cancer Institute and member of the Royal College of Physicians Tobacco Advisory Group, said.
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