Washington: Smoking reduces the production of a Fallopian tube ene known as “BAD,” increasing the risk of ectopic pregnancy, a new study has warned.The finding was made by scientists led by Drs Andrew Horne and Colin Duncan at the Medical Research Council (MRC) Centre for Reproductive Health in Edinburgh, UK.Ectopic pregnancy - when the embryo implants outside the uterus and in the Fallopian tube - occurs in up to 2 percent of all pregnancies and is the most common cause of maternal death in early pregnancy.There is currently no way to prevent an ectopic pregnancy, and the condition must be treated by abdominal surgery or, when the ectopic is small and stable, by injection of a drug called methotrexate.In presenting background information to the study, Dr Horne explained that ectopic pregnancy is the result of a combination of factors affecting the transport of the developing embryo from the Fallopian tube to the uterus and changes in the tubal environment, which allow early implantation to occur.Smoking is known to be a major risk factor, but how smoking changes the environment of the Fallopian tube for an ectopic pregnancy to occur has so far remained largely unknown.
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