A new study involving an Indian-origin researcher has suggested that taking a cholesterol-lowering drug called statin before having major elective surgery could potentially reduce serious kidney complications.
A total of 213,347 patients from 211 hospitals underwent major elective surgery, and 4,020 patients (1.9 per cent) developed postoperative kidney injury within two weeks of surgery. A total of 1,173 patients (0.5 per cent) required dialysis within two weeks of surgery, and 5,974 patients (2.8 per cent) died within a month of surgery. Prior to surgery, 67,941 patients (32 per cent) were taking a statin. Patients taking a statin were 20 per cent less likely to develop kidney injury, need dialysis, and die compared to patients who were not taking a statin. Also, there was evidence of a dose-effect, with patients on higher potency statins having less kidney injury. In addition, statins were beneficial whether they were started greater than 90 days or less than 30 days prior to surgery. The study appears in an upcoming issue of the Journal of the American Society Nephrology. ANI
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