Melbourne: Australian researchers are claiming to have managed to "trick" human kidney cells into reverting to generalised cells, able to develop into virtually any type of tissue in the body.
That is, if skin cells are used to create iPS cells for kidney research, they do not "remember" the defect causing the person`s inherited kidney disease.According to stem cell scientist Andrew Laslett with CSIRO Materials Science and Engineering and Monash University`s Department of Anatomy and Developmental Biology, until now stem cell researchers have avoided the kidney, as the organ is enormously complex, being made up of many cell types."Instead, they`ve gone for the low-hanging fruit," he said.Along with their Monash colleagues, researcher Ricardo and Laslett described their work this week, in the Journal of the American Society of Nephrology.They reported that they reprogrammed a type of kidney cell called a mesangial cell by using a virus to ferry a cocktail of four factors into it. They then demonstrated that de-specialised cells could develop normally into the beginning layers of a cell. PTI
Sleep deprivation leads to weight gain
Scientists discover gene that determines your intelligence