Tummy `clock` tells us how much to eat
Melbourne: Scientists have found the first evidence that the nerves in the stomach act as a circadian clock, limiting food intake to specific times of the day.
The discovery, by University of Adelaide researchers, could lead to new information about how the gut signals to our brains about when we're full, and when to keep eating.
In the University's Nerve-Gut Research Laboratory, Dr Stephen Kentish investigated how the nerves in the stomach respond to stretch, which occurs as a consequence of food intake, at three-hourly intervals across one day.
"These nerves are responsible for letting the brain know how much food we have eaten and when to stop eating," said Kentish, who is the lead author of the paper.
"What we've found is that the nerves in the gut are at their least sensitive at time periods associated with being awake. This means more food can be consumed before we feel full at times of high activity, when more energy is required," Kentish added.
"However, with a change in the day-night cycle to a period associated with sleeping, the nerves in the stomach become more sensitive to stretch, signalling fullness to the brain quicker and thus limiting food intake.
"This variation repeats every 24 hours in a circadian manner, with the nerves acting as a clock to coordinate food intake with energy requirements," he said.
So far this discovery has been made in laboratory studies, not in humans.
"Our theory is that the same variations in nerve responses exist in human stomachs, with the gut nerves being less sensitive to fullness during the day and more sensitive at night," Kentish said.
Study leader Associate Professor Amanda Page said this research could lead to further discoveries about how changes in people's circadian clocks affect their eating habits.
"We know that shift workers, for example, are more prone to disruptions in sleep and eating behaviour, leading to obesity and other health problems," Page said.
"We are now conducting further research to see what kind of impact such changes to the circadian rhythm will have on eating behaviour, and how the nerves in the stomach react to those changes," she said.
More from India
More from World
More from Sports
More from Entertaiment
- Vyapam Scam: IMA president Sudhir Tiwari fears life threat
- Vyapam Scam: Mystery over journalist Akshay Singh's death continues
- Panel discussion on RSS's 'Muslim Rashtriya Manch' first Iftaar party
- Jhansi police launches ‘Citizen Cop’ android app
- MPs spend more than Rs 25 cr taxpayers' money on study tours: DNA reports
- Vyapam scam: MP medical college dean found dead in hotel, body sent for post-mortem
- Vyapam scam: Last rites of journalist Akshay Singh performed; MP CM assures of SIT probe
- Photographer captures International Space Station flying across moon
- PM Narendra Modi holds talks with Uzbek leader
- Chile stun Argentina to win first Copa America crown