Bangalore: Scientists at the International Centre for Genetic Engineering and Biotechnology (ICGEB) in New Delhi have shown that tuberculosis may be diagnosed in future using a fast, inexpensive urine test.
"Among numerous volatile molecules present in urine samples, the levels of five VOCs were found to be significantly altered and together form a molecular signature that can accurately discriminate TB patients from non-TB individuals. We have demonstrated the potential of urinary VOCs as a TB disease marker," the researchers said in their paper.They said a major advantage of the proposed method is the non-invasive nature of urine collection. "Urine is a comparatively safer matrix as compared to sputum and painless in collection as compared to blood."TB strikes an estimated 10 million people and kills three million each year, mostly in developing countries, the scientists noted.Funding for their study was provided by the government of India`s Department of Biotechnology and International Centre for Genetic Engineering and Biotechnology.According to WHO, each year nearly 20 lakh people in India develop tuberculosis, of which 8.7 lakh are infectious cases. It is estimated that annually around 330,000 Indians die of the disease. The country accounts for one fifth of global tuberculosis cases. IANS
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