Washington: Researchers have found associations between plasma concentrations of saturated phospholipid fatty acids and risk of coronary heart disease, and an inverse association between omega-6 polyunsaturated phospholipid fatty acids and risk of coronary heart disease.
The findings by Kay-Tee Khaw of the University of Cambridge, UK and colleagues are based on the analysis of data from a prospective cohort study.
“Early guidelines to prevent [coronary heart disease] recommended reductions in saturated fat but little consistency as to what might be substituted: other fats, protein, or carbohydrate. Our results add to the accumulating evidence that substitution of saturated fat by n-6 polyunsaturated fat may have more [coronary heart disease] benefits,” the researchers said.
The study appeared in this week`s PLoS Medicine.