Why high-fat diet increases pre-eclampsia risk

Updated: Aug 09, 2013, 11:11 AM IST

Washington: Pre-eclampsia is a relatively common pregnancy disorder that is characterized by high blood pressure and high quantity of protein in blood.

In a recent study pregnant rats were fed a high-fat diet for 20 days.

The scientists found that these pregnant rats experienced preeclampsia-like syndromes such as hypertension and proteinuria.

Simultaneously, metabotropic glutamate receptor 1 mRNA and protein expressions were upregulated in the rat hippocampus.

These findings indicate that increased expression of metabotropic glutamate receptor 1 promotes the occurrence of high-fat diet-induced preeclampsia in pregnant rats.

Therefore, the control of fat intake is significant for the prevention of pregnancy-induced eclampsia.

The study has been published in the Neural Regeneration Research.