Washington: A new study by scientists from Berlin, Bonn and Dundee has shown that the diabetes drug Metformin has an effect against one of the main causes of the Alzheimer’s disease. Metformin, a drug used in type 2-diabetes, might have the potential to also act against Alzheimer’s disease. This has been shown in a study from scientists of the German Center for Neurodegenerative Diseases (DZNE), the University of Dundee and the Max-Planck-Institute for Molecular Genetics. The researchers have found that the diabetes drug metformin counteracts alterations of the cell structure protein Tau in mice nerve cells. These alterations are a main cause of the Alzheimer’s disease. Moreover, they uncovered the molecular mechanism of metformin in this process. “If we can confirm that metformin shows also an effect in humans, it is certainly a good candidate for an effective therapy on Alzheimer’s diseases,” says Sybille Krauß from DZNE.
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