Washington: With the help of drunken fruit flies, scientists have identified entire networks of genes—also found in humans—that play a key role in alcohol drinking behaviour. Researchers from North Carolina State and Boston universities say that this discovery provides a crucial explanation of why some people seem to tolerate alcohol better than others, as well as a potential target for drugs aimed at preventing or eliminating alcoholism.Also, this discovery sheds new light on many of the negative side effects of drinking, such as liver damage.
Armed with this information about fruit flies, the scientists set out to determine if the same genes contribute to alcohol drinking habits in humans. Indeed they do: expression of the human counterpart of a critical gene in fruit flies could be directly tied to alcohol consumption in humans, the researchers found.The study has been published in the October 2009 print issue of the journal Genetics. ANI
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