Mumbai: Tata Group promoted, AdvinusTherapeutics, announced the discovery of a novelmolecule for treatment of type II diabetes - GKM -001. It is the first Glucokinase modulator discoveredand developed in India. The molecule is an activator of glucokinase; an enzymethat regulates glucose balance and insulin secretion in thebody. GKM-001 is indigenously developed molecule and theinitial clinical trials have shown excellent results for bothsafety and efficacy, the company said in a statement here. "Considering past failures of other companies, ourdiscovery program primarily focused on identifying a moleculethat would be efficacious without causing hypoglycemia; a sideeffect associated with most compounds developed for thistarget," Advinus Therapeutics MD & CEO, Rashmi Barbhaiya said.
We are very proud that GKM-001 is 100 per cent Indian.Advinus`s discovery team in Pune discovered the molecule andentire pre-clinical development was carried out at our centrein Bangalore, he said.PTI
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