Zeenews Bureau London: In what may be bring tremendous relief to the diabetics who undergo the daily ordeal of taking insulin injections to keep their disease in check, a study published in Lancet says that just once weekly shot of exenatide can vastly help improve blood sugar control in people with type 2 diabetes produces a significant improvement in bloodsugar control, as well as inducing a mean weight loss of 2.6kg per patient. The current standard second-line therapy of insulin glargine(dosed to a specific target) also produces improved blood sugar control, but to a lesser extent than exenatide. Insulin glargine, which has to be injected daily, also produced a mean weight gain of 1.4kg per patient.
Dr Anoop Misra, the Director of Department of Diabetes & Metabolic Diseases, Fortis Hospital, New Delhi, India, agreed that exenatide could be used in patients "with obesity and those in whom hypoglycaemia is a clinical concern." According to him "Currently, there is more promise, few disadvantages, and some unknowns about treatment with long-acting exenatide for diabetes.” ”Despite advances in antihyperglycaemic therapy, a drug which would leadto substantial prevention of macrovascular and microvascularcomplications, decreases mortality, and is convenient and affordable, remains the undiscovered Holy Grail of diabetes management,” Dr Mishra said.
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