New Delhi: Researchers are working to develop a pill composed of leptin, the protein that tells our brain to stop eating and, hence, reverse obesity.
The new pill, under creation, is based on a startling U-M discovery from 2006: Leptin isn`t only secreted by fatty tissues. "From the first bite of any meal, leptin levels skyrocket in the bloodstream. Yet this has nothing to do with the leptin stored in the fatty tissues," says Bendayan. "In the lab, we proved that up to 80 percent of cells in our stomach also produce leptin. Those are the ones that regulate appetite," Bendayan adds, according to a U-M release. The U-M finding led to a different understanding of how the protein works, since leptin alone can`t survive in an acidic stomach without assistance. Indeed, leptin protects itself with an accomplice that acts as its bodyguard and accompanies the protein through the digestive system until it can be absorbed into the bloodstream.IANS
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