Washington: Scientists from Albany Medical College, New York, are one step closer in developing a nasal spray that is more effective against flu, pneumonia and even bioterrorism agents, such as Yersinia pestis that causes the plague, than an injection. They showed how including a natural immune chemical with standard vaccines could boost their protective effect when delivered through the nose.The respiratory tract is a major entry site for various viral and bacterial pathogens.
Nasal vaccines could have a number of other advantages over vaccines that must be injected. "Vaccination via a nasal spray is a non-invasive procedure that is easier than administering vaccines by injection. In addition our results have shown that antibodies induced by intranasal vaccination are effective not only in preventing infection but can also protect the pulmonary tract in a therapeutic manner after pathogen exposure," explained Metzger. "In the case of a bioterrorism threat or an influenza pandemic, this is significant,’ added Metzger.The study was presented at the Society for General Microbiology``s Spring Conference in Harrogate. ANI
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