Washington: Till date, the biological mechanisms behind stress affecting tumour`s ability to grow and spread in cancer patients were not well understood.
In the current study, Fang and colleagues looked at 37 newly diagnosed, pre-surgical head and neck cancer patients, to see if psychosocial functioning, such as perceived stress and depressive factors, was associated with VEGF, a biological pathway relating to patient outcomes. "Our analysis indicated that higher levels of perceived stress and depressive symptoms were associated with greater VEGF expression in the tumour tissue of these patients" said Fang. Greater VEGF expression was, in turn, associated with shorter disease-free survival among patients.The study has been presented at the 32nd Annual Meeting and Scientific Sessions of the Society of Behavioural Medicine. ANI
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