Washington: New research has revealed that a sugar found in mouse breast milk promotes the generation of colitis in offspring. Sugars in breast milk are essential for the development of the newborn immune system and the growth of beneficial commensal bacteria in the gut. But certain milk sugars in certain contexts could be bad news. The team led by Thierry Hennet at the University of Zurich found that newborn mice fostered by mothers lacking one particular milk sugar—sialyl(alpha2,3)lactose—were less susceptible to inflammation-induced colitis later in life. The resistance to colitis was attributed to differences in the commensal bacteria.
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