Sydney: Australian researchers may have come closer to developing a male contraceptive pill.They have discovered a way to cut off the fuel supply to the “motor” that drives human sperm, greatly reducing their swimming ability and opening a new avenue to developing a male pill.The finding also throws new light on the little-understood reasons for infertility in men, the Sydney Morning Herald reported.Led by Moira O’Bryan, of Monash University’s school of biomedical sciences, the research used mice in laboratory tests with scientists engineering mutation in a gene called RABL2 that delivers protein fuel to the engine in a sperm’s tail.The mutation resulted in sperm tails that were 17 per cent shorter than normal and a 50 per cent reduction in sperm production.The most striking result was that all mice with the mutated gene were rendered infertile and their sperm incapable of swimming.“They weren’t wriggling or going anywhere, they were just twitching. With this mutation, we get motors that don’t work properly.
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