Estate agents are even willing to do a "two for the price of one" as the desperate owners are also auctioning a similar house in the road for about 1,000 pounds.
Both the houses are in an area blighted by arson and anti-social behaviour, and have their windows barred against vandalism, the auctioneers admitted.
However, they have attracted red-hot interest with one man making a 1046 kilometres round trip for a viewing 'The Mirror' reported.
"There's no reserve price, which is unusual. We are looking for a quick sale and may do a 'buy one get one free'," Estate agent Richard Watson said.
"We believe 750 pounds is the cheapest house even in the current market.
"Let's face it, you couldn't get a banger for that - you're probably looking at a very posh fridge freezer," he said.
Similar houses to the 750-pound pad in Port Clarence, near Middlesbrough, would usually sell for 35,000 pounds.
Estate agents Robinsons admits the area is not great and empty houses in the road tend to get vandalised.
"You can get let them for 100 pounds-a-week so it's a good investment," Watson added.
He said that a lorry driver from Portsmouth has already been for a viewing and is keen to uproot his family.
London: Britain's cheapest house - a three-bed semi in Teesside - is going under the hammer for a meagre 750 pounds.
First Published: Tuesday, October 02, 2012, 16:00