Lacrosse players from Seton Hill University and three coaches were among the 23 people aboard when the bus crashed on Saturday at about 9 am, local time, turnpike spokeswoman Renee Colborn said.
It's not clear what caused the crash, but state police were investigating, said Megan Silverstram of the Cumberland County public safety department.
Kristina Quigley, 30, of Greensburg, Pennsylvania, was flown to a hospital and died there from injuries from the crash, Cumberland County authorities said.
They say Quigley was about six months pregnant and her unborn child did not survive. The driver, 61-year-old Anthony Guaetta of Johnstown, Pennsylvania, died at the scene of the crash.
Two other injured passengers were flown by helicopter to Penn State Hershey Medical Center, hospital spokeswoman Danielle Ran said. She did not give their conditions.
Officials said all the other passengers were taken to hospitals as a precaution. The bus came to a stop upright on the side of the road with part of its left side shorn off, photos from the scene showed, though it's unclear whether that was from the impact or rescue operation.
The bus operator, Mlaker Charter & Tours, of Davidsville, Pennsylvania, sent investigators to the scene, company dispatcher Kelly Hay said. The company had no information yet from the investigators and could not comment, she said.
The company is up to date on its inspections, which include bus and driver safety checks, said Jennifer Kocher, a spokeswoman for the state Public Utility Commission, which regulates bus companies.
The agency's motor safety inspectors could think of no accidents or violations involving the company that would raise a red flag, she said, though complete safety records were not available on Saturday.
State environmental officials were also sent to the scene because of a diesel fuel spill from the bus.
Seton Hill is a Catholic school of about 2,500 students near Pittsburgh. The team was to play Saturday afternoon at Millersville University, about 50 miles (80 kilometres) from the crash site in central Pennsylvania.
Counseling service will be provided for students and others, the school said, and an administrator was headed to the scene of the crash to help students and their families there.
Carlisle: A tour bus carrying a college's women's lacrosse team to a game went off a highway in Pennsylvania and crashed into a tree, killing a pregnant coach and the driver and sending others to hospitals, authorities have said.
First Published: Sunday, March 17, 2013, 08:18