Madrid: Former world number one Andy Roddick was dumped out in the first round of the Madrid Open, upset 6-4, 6-7, 6-3 by qualifier Flavio Cipolla.
The American 12th seed, who lost to Roger Federer in the quarter-finals two years ago on his most recent appearance at the clay event, had his serve broken four times by the Italian ranked 148 places below him at number 160.
Roddick`s friend and compatriot Mardy Fish, the 12th seed, was also eliminated in the first round, losing 7-6, 4-6, 7-6 to fellow American John Isner.
Qualifier Thiemo de Bakker of the Netherlands fought back to beat former world number one and wild card Juan Carlos Ferrero 2-6, 7-5, 6-4, while ninth-seeded Frenchman Gael Monfils defeated big-serving Croat Ivo Karlovic 6-3, 7-6.
World number one and top seed Rafa Nadal, who has a bye into the second round, will play Marcos Baghdatis after the former Australian Open finalist edged past Colombian qualifier Alejandro Falla 6-3, 3-6, 7-6.
Novak Djokovic and Roger Federer, the second and third seeds, also play their opening matches on Wednesday.