New York: Stan Wawrinka reached the US Open semi-finals on Wednesday with a 6-4, 6-4, 6-0 rout of South Africa`s Kevin Anderson to set-up a possible clash with compatriot Roger Federer.
French Open champion Wawrinka booked a spot in his second US Open last-four match, having also reached the same stage in 2013.
Anderson, the 15th seed and playing in his first Grand Slam quarter-final, had knocked out third seed Andy Murray in the previous round.
That effort seemed to take its toll as he committed 42 unforced errors and carved out just a single break point against the fifth-seeded Wawrinka, who romped to victory in just 107 minutes.
The result shattered 29-year-old Anderson`s hopes of becoming the first South African in the semi-finals in New York since Johan Kriek in 1980.
If five-time champion Federer sees off French 12th seed Richard Gasquet in his quarter-final, it will set up an intriguing battle of close friends.
Federer has a 16-3 career lead over Wawrinka, his Davis Cup-winning teammate, but Wawrinka won their last clash in the French Open quarter-finals this year.
Anderson had won four of his last seven meetings with Wawrinka but he was horribly out of sorts on Wednesday, dropping serve in the seventh game of the first set and ninth of the second.
The third set was all over in 25 minutes with Anderson winning just five points.