Yates made the decisive break in the closing stages of the 163.2km stage from Monforte de Lemos to take victory in a time of 4hr 05min from Spain`s Luis Leon Sanchez and Italian Fabio Felline.
Froome, who was also champion in 2013 and last year, finished ahead of Frenchman Romain Bardet in second and Nairo Quintana of Colombia in third.
But with only Sunday`s virtual procession into Paris to come, the Tour is all but over.
Bardet finished 23sec ahead of Joaquim Rodriguez after attacking on a slippery and dangerous descent where several of his rivals crashed.
Quintana, who was the first to respond to Porte`s attack and then Froome`s counter, cracked badly and lost 28sec to the race leader.
The Slovak Tinkoff rider sprinted to victory in the 106-mile (170.5km) first stage held in and around San Diego, finishing clear of Dutch duo Wouter Wippert and Dylan Groenewegen.
The 20-year-old from Andaman and Nicobar collected 211 points in 500m time trial and secured fourth place in the World Elite UCI.
Indian contingent won five medals on the opening day of the Track Asia Cup in Delhi.
Veteran cyclist says here was something wrong with the guiding vehicle and referees.
The last three Olympic men's mountain bike champions will be among the competitors at the sport's test event in Rio de Janeiro on Sunday.
Disgraced former cyclist Lance Armstrong has paid out over $10 million (8.9 million euros) in a settlement to Bob Hamman and his SCA Promotions company, British newspaper the Sunday Times reported.
Vasil Kiryienka, the European Games time-trial champion from Belarus, captured the men`s individual time-trial crown Wednesday at the World Road Cycling Championships
New Zealand`s Linda Villumsen powered to victory in the road cycling world championship individual time trial on Tuesday, claiming the title that had always eluded her.
The International Cycling Union (UCI) approved a series of sweeping reforms for men`s road cycling, including an overhaul of the World Tour schedule, the sport`s governing body said on Tuesday.
Italy`s 2014 Tour de France champion Vincenzo Nibali leads a strong field into the inaugural Tour of Abu Dhabi, which begins on October 8th, while Britain`s star sprinter Mark Cavendish and Spaniard Alejandro Valverde will also be on the start-line.
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