Due to his mental instability, Deadpool hears multiple inner voices all the time. These voices engage him in bizarre and amusing conversations with himself.
The source of Deadpool's healing ability is an unsuccessful attempt to treat his deadly cancer. Although it keeps him alive, the ongoing battle between his cancer and healing factor leaves his body horribly disfigured.
Chimichangas are one of Deadpool's favorite dishes, but he's been known to joke that he prefers to pronounce the term than actually eat the food.
Deadpool is practically immortal thanks to a curse from Thanos and his healing factor. Because of his jealousy over Deadpool's relationship with Death, the cosmic being, Thanos cursed him, keeping him from passing away.
Because he regularly breaks the fourth wall, Deadpool is known for acknowledging that he is a fictional character from a comic book. He frequently addresses the crowd directly while offering a lighthearted meta-narrative.
Deadpool can heal from any wound, even beheading and burning. He also can restore entire limbs that he lost in battle. Deadpool's enhanced healing factor is on par with or even greater than Wolverine.
At first, Deadpool was meant to be a spoof of Deathstroke from DC Comics. Wade Wilson, his true name, is a parody of Slade Wilson from Deathstroke.