Serena Williams' biggest Grand Slam loss was a first round loss to Virginie Razzano of France in the 2012 French Open. (Source: Twitter)
A second round loss in 1998 Australian Open was Serena Williams' worst show at Melbourne. It was the American legend's Grand Slam debut. (Source: Twitter)
Serena Williams also lost in second round in 2014 French Open, her second worst performance at Roland Garros. (Source: Twitter)
Serena Williams has lost in Wimbledon third round thrice, in 1998, 2005 and 2014. (Source: Twitter)
Serena Williams' worst performance in her home Grand Slam, the US Open, was a third round exit in 1998 on debut. (Source: Twitter)