Washington: Two US police officers were injured and a suspect killed during a shoot-out in the city of Boston, authorities said.

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The police officers were fired at on Wednesday night when they responded to a call about a "person with a gun", the police confirmed.

Boston Police Commissioner William Evans told reporters that one officer was shot multiple times and was in a critical condition, and the other officer was in stable condition, NBC News reported.

The officers were responding to a call about a person with a gun at a Gladstone street address at 10.51 p.m. when "officers came under fire", Evans said on Twitter.

One suspect was killed, Evans told reporters, adding that the call the officers were responding to was possibly a domestic incident.

"Commanding officers, they moved in and neutralised the threat pretty quick that no one else got killed," Evans said.

Boston Police on Twitter told residents to "shelter in place" and that a search for a suspect was underway, but said around 30 minutes later that the order was lifted and one suspect was located.