Beirut: At least 47 fighters were killed in clashes between the Islamic State group and Syrian insurgents, a monitor said on Saturday, in an area where the United States and Turkey are planning to open a new front against the ultra-hardline group.

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The renewed fighting raged on Friday around the rebel-held town of Marea, 20 km (12 miles) from the Turkish border, the Britain-based Syrian Observatory for Human Rights said.

The area falls within a "safe zone" Turkey said last month it would set up in northern Syria to help keep Islamic State at bay.